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Christelle Monville


Christelle Monville

University of Evry Val d' Essonne, France

Biography

Christelle Monville has completed his PhD at the age of 28 years from Créteil University and postdoctoral studies from Cardiff University. Christelle Monville is a current professor at Evry’s University (France). The objectives of her group (Istem, www.istem.eu) are (1) to develop pre-clinical studies required for the development of human pluripotent stem cells cellular therapy for the treatment of a number of monogenic retinal diseases and (2) disease modeling and drug discovery using patient-specific human induced Pluripotent Stem (hiPS). Recently, her group has successfully developed, under clinically compatible conditions, a tissue-engineered product (TEP) consisting of RPE cells derived from hESCs disposed on a biocompatible substrate. These results are supportive for the initiation of our phase I/II clinical trial to treat RP patients.

Abstract

Abstract : Preclinical validation of a tissue engineered product consisting in RPE derived from human embryonic stem cells disposed on human amniotic membrane in rats and non-human primates