Tissue Engineering and Regenerative Medicine

Fundamentals of Tissue Engineering

Tissue engineering is a multidisciplinary field that combines principles of biology, materials science, and engineering to create functional tissues for repairing or replacing damaged organs. The process involves using living cells, biocompatible scaffolds, and bioactive molecules to support cell growth and tissue development. Scaffolds mimic the extracellular matrix, providing structural support and guiding cell behaviour for regeneration. Critical components include understanding cellular interactions, material properties, and biochemical signalling. Advances in stem cells, biomaterials, and 3D bio printing have expanded its applications, from skin grafts to organ reconstruction, offering innovative solutions for regenerative medicine and reducing the dependence on donor transplants.