Tissue Engineering and Regenerative Medicine

Organs-on-Chips and Micro physiological Systems

Organs-on-chips (OoCs) and microphysiological systems (MPS) are innovative bioengineering platforms that simulate the structure and function of human organs on microfluidic devices. These systems integrate living cells, biomaterials, and microchannels to recreate the cellular architecture, mechanical forces, and biochemical environments of specific tissues or organs.

OoCs enable the study of organ-specific responses to drugs, diseases, and toxins in a controlled, human-relevant context, reducing reliance on animal testing. MPS expands this concept by connecting multiple organ chips, mimicking systemic interactions like metabolism and drug distribution. Applications include precision medicine, disease modeling, drug development, and advancing personalized therapeutic strategies.